Figure 6 | Scientific Reports

Figure 6

From: Increased estrogen to androgen ratio enhances immunoglobulin levels and impairs B cell function in male mice

Figure 6

IgE class switching was significantly enhanced in the splenocytes isolated from AROM+ males compared to cells from WT males. (A) Proliferation of B cells after IgE class switching (mean ± SD, n = 6), (B) The secretion of IgE in B cells after class switching (mean ± SD, n = 6). (C) The relative amount of CD19 positive B cells in the AROM+ and WT splenocytes after the class switching. N.S.: no stimulation, data presented as median and interquartile range, Mann–Whitney test P: ≤ 0.05 (*), and ≤ 0.001 (***).

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