Table 1 Baseline characteristics of the study population according to the tertiles of gamma-glutamyl transferase.
Characteristics | Overall (nā=ā5,120) | Gamma-glutamyl transferase | Ā | ||
|---|---|---|---|---|---|
Tertile 1 āā¤ā15Ā IU/L (nā=ā1618) | Tertile 2 16ā27Ā IU/L (nā=ā1791) | Tertile 3 āā„ā28Ā IU/L (nā=ā1711) | p value | ||
Age, years | 53 (49ā58) | 53 (49ā59) | 54 (50ā59) | 53 (49ā57) | ā<ā0.001 |
Male sex, no. (%) | 3486 (68.1) | 618 (38.2) | 1364 (76.2) | 1504 (87.9) | ā<ā0.001 |
Body mass index, kg/m2 | 24.3 (22.5ā26.2) | 23.0 (21.2ā24.7) | 24.5 (22.8ā26.2) | 25.5 (23.8ā27.2) | ā<ā0.001 |
Waist circumference, cm | 85 (80ā90) | 80 (75ā86) | 86 (80ā90) | 89 (84ā93) | ā<ā0.001 |
Systolic blood pressure, mmHg | 119 (110ā128) | 115 (107ā124) | 119 (110ā128) | 122 (113ā130) | ā<ā0.001 |
Diastolic blood pressure, mmHg | 76 (69ā83) | 72 (65ā79) | 76 (69ā83) | 79 (73ā86) | ā<ā0.001 |
Diabetes mellitus, no. (%) | 772 (15.1) | 147 (9.1) | 280 (15.6) | 345 (20.2) | ā<ā0.001 |
Hypertension, no. (%) | 1778 (34.7) | 406 (25.1) | 634 (35.4) | 738 (43.1) | ā<ā0.001 |
Hyperlipidemia, no. (%) | 1559 (30.4) | 358 (22.1) | 555 (31.0) | 646 (37.8) | ā<ā0.001 |
Current smoker, no. (%) | 1024 (20.0) | 136 (8.4) | 371 (20.7) | 517 (30.2) | ā<ā0.001 |
Obesity, no. (%) | 2114 (41.3) | 362 (22.4) | 756 (42.3) | 996 (58.2) | ā<ā0.001 |
Family history of coronary artery diseasea, no. (%) | 788 (15.4) | 252 (15.6) | 282 (15.7) | 254 (14.8) | 0.739 |
Fasting blood glucose, mg/dL | 99 (93ā108) | 96 (91ā102) | 100 (94ā109) | 103 (96ā114) | ā<ā0.001 |
Total cholesterol, mg/dL | 193 (172ā217) | 190 (171ā214) | 192 (171ā214) | 198 (176ā221) | ā<ā0.001 |
Low-density lipoprotein cholesterol, mg/dL | 120 (101ā120) | 117 (99ā136) | 121 (102ā140) | 123 (104ā143) | ā<ā0.001 |
High-density lipoprotein cholesterol, mg/dL | 51 (43ā61) | 57 (48ā68) | 49 (43ā60) | 48 (41ā56) | ā<ā0.001 |
Triglycerides, mg/dL | 108 (78ā156) | 84 (64ā113) | 109 (81ā151) | 138 (100ā201) | ā<ā0.001 |
Creatinine, mg/dL | 0.9 (0.8ā1.0) | 0.8 (0.7ā0.9) | 0.9 (0.8ā1.0) | 0.9 (0.9ā1.0) | ā<ā0.001 |
Uric acid, mg/dL | 5.5 (4.5ā6.4) | 4.7 (3.9ā5.6) | 5.6 (4.8ā6.4) | 6.0 (5.2ā7.0) | ā<ā0.001 |
Aspartate aminotransferase, IU/L | 25 (21ā31) | 22 (19ā26) | 24 (21ā29) | 28 (24ā36) | ā<ā0.001 |
Alanine aminotransferase, IU/L | 22 (16ā31) | 17 (13ā21) | 22 (17ā29) | 30 (22ā43) | ā<ā0.001 |
High-sensitivity C-reactive proteināā„ā2Ā mg/L | 47 (0.9) | 7 (0.4) | 21 (1.2) | 19 (1.1) | 0.046 |