Table 1 Baseline characteristics of the study population according to the tertiles of gamma-glutamyl transferase.

From: Association of gamma-glutamyl transferase with subclinical coronary atherosclerosis and cardiac outcomes in non-alcoholics

Characteristics

Overall

(n = 5,120)

Gamma-glutamyl transferase

Ā 

Tertile 1

 ≤ 15Ā IU/L (n = 1618)

Tertile 2

16–27Ā IU/L (n = 1791)

Tertile 3

 ≄ 28Ā IU/L (n = 1711)

p value

Age, years

53 (49–58)

53 (49–59)

54 (50–59)

53 (49–57)

 < 0.001

Male sex, no. (%)

3486 (68.1)

618 (38.2)

1364 (76.2)

1504 (87.9)

 < 0.001

Body mass index, kg/m2

24.3 (22.5–26.2)

23.0 (21.2–24.7)

24.5 (22.8–26.2)

25.5 (23.8–27.2)

 < 0.001

Waist circumference, cm

85 (80–90)

80 (75–86)

86 (80–90)

89 (84–93)

 < 0.001

Systolic blood pressure, mmHg

119 (110–128)

115 (107–124)

119 (110–128)

122 (113–130)

 < 0.001

Diastolic blood pressure, mmHg

76 (69–83)

72 (65–79)

76 (69–83)

79 (73–86)

 < 0.001

Diabetes mellitus, no. (%)

772 (15.1)

147 (9.1)

280 (15.6)

345 (20.2)

 < 0.001

Hypertension, no. (%)

1778 (34.7)

406 (25.1)

634 (35.4)

738 (43.1)

 < 0.001

Hyperlipidemia, no. (%)

1559 (30.4)

358 (22.1)

555 (31.0)

646 (37.8)

 < 0.001

Current smoker, no. (%)

1024 (20.0)

136 (8.4)

371 (20.7)

517 (30.2)

 < 0.001

Obesity, no. (%)

2114 (41.3)

362 (22.4)

756 (42.3)

996 (58.2)

 < 0.001

Family history of coronary artery diseasea, no. (%)

788 (15.4)

252 (15.6)

282 (15.7)

254 (14.8)

0.739

Fasting blood glucose, mg/dL

99 (93–108)

96 (91–102)

100 (94–109)

103 (96–114)

 < 0.001

Total cholesterol, mg/dL

193 (172–217)

190 (171–214)

192 (171–214)

198 (176–221)

 < 0.001

Low-density lipoprotein cholesterol, mg/dL

120 (101–120)

117 (99–136)

121 (102–140)

123 (104–143)

 < 0.001

High-density lipoprotein cholesterol, mg/dL

51 (43–61)

57 (48–68)

49 (43–60)

48 (41–56)

 < 0.001

Triglycerides, mg/dL

108 (78–156)

84 (64–113)

109 (81–151)

138 (100–201)

 < 0.001

Creatinine, mg/dL

0.9 (0.8–1.0)

0.8 (0.7–0.9)

0.9 (0.8–1.0)

0.9 (0.9–1.0)

 < 0.001

Uric acid, mg/dL

5.5 (4.5–6.4)

4.7 (3.9–5.6)

5.6 (4.8–6.4)

6.0 (5.2–7.0)

 < 0.001

Aspartate aminotransferase, IU/L

25 (21–31)

22 (19–26)

24 (21–29)

28 (24–36)

 < 0.001

Alanine aminotransferase, IU/L

22 (16–31)

17 (13–21)

22 (17–29)

30 (22–43)

 < 0.001

High-sensitivity C-reactive protein ≄ 2Ā mg/L

47 (0.9)

7 (0.4)

21 (1.2)

19 (1.1)

0.046

  1. Values are presented as median (interquartile range) or number (%).
  2. Pearson's chi-square test or Fisher's exact test were used for categorical variables and one-way analysis of variance or Kruskal–Wallis test were used for numerical variables.
  3. aCoronary artery disease in a first-degree relative of any age.