Table 3 Multidimensional logistic regression model evaluating BDG test quality and other possible influencing parameters in prediction of proven and probable IFD—galactomannan test excluded.

From: Bronchoalveolar lavage fluid and serum 1,3-β-d-glucan testing for invasive pulmonary aspergillosis diagnosis in hematological patients: the role of factors affecting assay performance

 

Estimate βi

Std. error

p

eβi

Antifungals administration

− 2.300

1.845

0.2125

0.10026

BALF BDG

0.0179

0.005820

0.0428

1.0181

Serum BDG

0.002836

0.001454

0.0511

1.0028

Bacteria in BALF

− 0.4843

0.7061

0.4928

0.61613

Bacteremia

− 15.67

1125

0.9889

1.57 × 10–7

Absolute neutrophil count

− 0.2840

0.1721

0.0990

0.75277

Aspirated BALF volume

− 0.01266

0.01222

0.3002

0.98742

Interaction BALF BDG and BALF volume

− 0.0001286

0.00007475

0.0854

0.99987

  1. BDG, 1,3-β-d-glucan; BALF, bronchoalveolar lavage fluid; IFD, invasive fungal disease; βi, regression coefficient; std. error, standard error; eβ, the chance that the episode will be closed as proven or probable IFD.
  2. AIC = 150.66; χ2 = 31.38; R2 ≈ 0.19.
  3. Bold value indicates statistical significance (p < 0.05).
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