Figure 3
From: Low dose amiodarone reduces tumor growth and angiogenesis
Amiodarone affects HUVEC function. (A) Viability assay of HUVECs, using WST8, after 24 and 72 h of incubation with ranging concentrations of Amiodarone (0, 0.1, 1, 3, 5, 7, and 10 μM), investigating cytotoxic and proliferation-rate effects, respectively, n = 8. ***p < 0.001, compared with untreated control cells with the same incubation time. (B, C) Scratch assay of HUVECs after 36 h of incubation using the IncuCyte S3 Live-Cell Analysis System, with ranging concentrations of Amiodarone (0, 1, 5, 7, and 10 μM), n = 8. Scale bar: 400 µm. *p < 0.05, ***p < 0.001, compared with non-treated control cells. Results are presented as mean ± SEM. Figure supplement 1. Amiodarone reduces cell viability of endothelial, fibroblast and melanoma cells.
