Figure 3
From: Toxicological evaluation of the ultrasonic extract from Dichroae radix in mice and wistar rats
Histopathological analysis of organs in the control (C) and three UEDR-treated groups (high dose, H; middle dose, M; low dose, L) after 28-day administration (H&E stained), scale bar = 50 µm. Livers (LI, 400 ×), kidney (KI, 400 ×), spleen (SP, 400 ×), lung (LU, 100 ×), and heart (HE, 400 ×) (A: Congestion; B: Granular degeneration; C: Vacuolar degeneration; D: Necrosis; E: Granular degeneration in renal tubular epithelial cells; F: Necrosis of splenic lymphocytes; G: Bronchial pneumonia; H: Interstitial pneumonia; J: Myocardial degeneration, slight).
