Figure 4 | Scientific Reports

Figure 4

From: CUX2, BRAP and ALDH2 are associated with metabolic traits in people with excessive alcohol consumption

Figure 4

The X axis represents the weights, which are the ridge coefficients (\(\hat{\beta}^{ridge}\)) corresponding to 48 SNPs. The Y axis represents the shrinkage parameter λ, which controls the size of the coefficients and the amount of regularisation. Curves of the ridge coefficients as a function of regularisation. Note that rs7398833, rs671 and rs3782886 have \(\hat{\beta}^{ridge}\) values that are maximal values away from zero and remain constant across different λ values. Those curves sharply alienated from X axis indicate dependent signals of linkage disequilibrium.

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