Figure 1
From: Increased intestinal permeability and gut dysbiosis in the R6/2 mouse model of Huntington’s disease

Intestinal permeability is increased in R6/2 mice. Intestinal permeability measured by determining the concentration of FD4 in the serum of R6/2 mice vs. wild type (WT) littermates at 16 weeks of age 4 h after oral FD4 administration. Data represent mean ± SEM, N = 10 for WT; N = 10 for R6/2; unpaired t test; *p ≤ 0.05. FD4 = Fluorescein Isothiocyanate-dextran.