Table 1 Clinical characteristics and comprehensive geriatric assessment according to the risk of CHA2DS2-VASc score.

Variables	Total (N = 117)	Intermediate risk of CHA₂DS₂-VASc (n = 13)	High risk of CHA₂DS₂-VASc^† (n = 104)	p value
Demographics
Age (year)	78 (74–82)	72 (70.5–74)	78.5 (76–83)	*< 0.001*
Sex, female (%)	53 (45.3%)	6 (46.2%)	47 (45.2%)	0.948
BMI, kg/m²	25.2 (23.0–27.1)	25.2 (22.2–27.4)	25.1 (23.0–27.0)	0.752
Medication and risk stratification
Antiplatelet use	57 (48.7%)	9 (69.2%)	48 (46.2%)	0.147
Anticoagulation use	65 (55.6%)	4 (30.8%)	61 (58.7%)	0.076
Elevated HAS-BLED risk (≥ 3)	29 (24.8%)	1 (7.7%)	28 (26.9%)	0.181
Comprehensive geriatric assessment
CCI	1 (0–2)	0 (0–1.5)	1 (0–2)	*0.048*
ADL dependency	13 (11.1%)	0 (0%)	13 (12.5%)	NA
IADL dependency	21 (17.9%)	0 (0%)	21 (20.2%)	NA
TUGT^‡	13 (10–14)	10 (9–12)	13 (11–14.75)	*0.004*
Gait speed^§	0.98 (0.79–1.17)	1.23 (0.96–1.41)	0.97 (0.75–1.14)	*0.007*
Grip strength	24.5 (18.9–30.8)	30.1 (22.1–39.6)	24.1 (18.4–30.5)	0.120
MMSE-KC	26 (22–28)	28 (25.5–28)	26 (22–28)	0.161
SGDS-K^¶	3 (1–7)	2 (0–2.5)	3 (1–7.5)	*0.025*
MNA	26 (23–27)	28 (26.3–28)	25.5 (22.5–27)	*0.001*
Polypharmacy (≥ 5 drugs)	86 (73.5%)	4 (30.8%)	82 (48.8%)	*0.001*
Frailty index	0.06 (0–0.17)	0 (0–0.06)	0.06 (0–0.19)	*0.007*

Data are presented as median (25–75th percentiles) or number of participants (percentages).
^†High risk of CHA₂DS₂-VASc score refers to score ≥ 2 in men or ≥ 3 in women and intermediate risk of CHA₂DS₂-VASc score refers to score 1 in men or score 2 in women.
^‡Data were missing for 12 patients.
^§Data were missing for seven patients.
^¶Data were missing for three patients.
ADL, activity of daily living; BMI, body mass index; CHA₂DS₂-VASc, congestive heart failure, hypertension, age ≥ 75 (doubled), diabetes mellitus, prior stroke or transient ischemic attack (doubled), vascular disease, age 65–74, female; CCI, Charlson Comorbidity Index; HAS-BLED, Hypertension, Abnormal renal/liver function, Stroke, Bleeding history or predisposition, Labile INR, Elderly, Drugs/alcohol concomitantly; IADL, instrumental activity of daily living; MMSE-KC, Korean version of Mini–Mental State Examination; MNA, Mini Nutritional Assessment; SGDS-K, short form of the Korean Geriatric Depression Scale; TUGT, timed up and go test.

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