Figure 1 | Scientific Reports

Figure 1

From: Protective effect of epigallocatechin-3-gallate (EGCG) on toxic metalloproteinases-mediated skin damage induced by Scyphozoan jellyfish envenomation

Figure 1

Inhibitory effects of EGCG on the proteolytic activity and the cytotoxicity of NnV. (A) NnV (4 μg) was loaded and run on SDS-PAGE, followed by gelatin zymography in reaction buffers containing various concentrations of EGCG (0.1, 0.3 and 1 mM). To examine the effect of EGCG on NnV-induced cell death, HaCaT cells (B) or HDF cells (C) were treated with the indicated concentrations of EGCG before or after NnV exposure (30 μg/ml) with 30 min. interval. Data represent as mean ± SD from three independent experiments performed on different well replicates. *p < 0.01 compared with vehicle control. #p < 0.01 compared with NnV alone.

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