Table 1 Baseline patient characteristics by NLR and SII status.

From: Inflammatory indexes as predictive factors for platinum sensitivity and as prognostic factors in recurrent epithelial ovarian cancer patients: a MITO24 retrospective study

Patient characteristics

NLR

p

SII

p

 < 3

 ≥ 3

 < 730

 ≥ 730

No. (%)

No. (%)

No. (%)

No. (%)

Median age, years [range]

60 [19–83]

64 [32–85]

0.066

58 [31–83]

64 [19–85]

0.012

Performance Status (ECOG)

 0

147 (68.7)

79 (51.3)

0.0007

111 (73.5)

115 (53.0)

 < 0.0001

 1–2

67 (31.3)

75 (48.7)

 

40 (26.5)

102 (47.0)

 

EOC histology

 Other

65 (29.5)

49 (31.6)

0.669

51 (32.7)

63 (28.8)

0.416

 Serous

155 (70.5)

106 (68.4)

 

105 (67.3)

156 (71.2)

 

Stage

 III

163 (74.1)

102 (65.8)

0.083

118 (75.6)

147 (67.1)

0.074

 IV

57 (25.9)

53 (34.2)

 

38 (24.4)

72 (32.9)

 

Ascites

 No

113 (53.0)

66 (42.6)

0.047

83 (54.2)

96 (44.6)

0.070

 Yes

100 (47.0)

89 (57.4)

 

70 (47.8)

119 (55.4)

 

BRCA status

 Wild type

42 (63.6)

21 (80.8)

0.113

31 (63.3)

32 (74.4)

0.253

 Mutated

24 (36.4)

5 (19.2)

 

18 (36.7)

11 (25.6)

 

 Unknown

154

129

 

107

176

 

Treatment

 CT

181 (82.3)

120 (77.4)

 

124 (79.5)

177 (80.8)

 

 CTB

39 (17.7)

35 (22.6)

0.245

32 (20.5)

42 (19.2)

0.749

  1. BRCA, BReast CAncer susceptibility gene; CT, chemotherapy; CTB, chemotherapy with bevacizumab; NLR, neutrophil-to-lymphocyte ratio; SII, systemic immune-inflammation index.