Figure 9 | Scientific Reports

Figure 9

From: Magnesium-alloy rods reinforced bioglass bone cement composite scaffolds with cortical bone-matching mechanical properties and excellent osteoconductivity for load-bearing bone in vivo regeneration

Figure 9

Immunohistochemical analyses. (A) Immunohistochemical images of OCN, COL1a1 and BMP2 expressed in newly-formed bone in defected area (blue arrowheads indicate the expression region of each protein). Integrated optical density (IOD) value measured by image analysis of OCN (B), COL1a1 (C) and BMP2 (D) (*p < 0.05, **p < 0.01, and ***p < 0.001 versus the indicated group). The bone defects in control group were kept empty.

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