Figure 4
From: Defining the structural basis for human leukocyte antigen reactivity in clinical transplantation
Prozone effect observed for 2E3-IgG1 at increasing concentrations as identified by the SAB assay. MFI of 2E3-IgG1 at 1 μg/mL, 2 μg/mL, 10 μg/mL and 50 μg/mL were connected with lines and plotted against the allele for both tests performed (A) at HSA and (B) at SHI. All 2E3-reactive HLA Class I alleles, two cross-reactive alleles (A*02:01 and A*66:02) and two non-reactive alleles (A*30:01 and A*30:02) are shown in the figure. SAB single antigen beads; MFI mean fluorescence intensity; HSA Heath Sciences Authority, Singapore; SHI Shared Health Inc., Canada; HLA human leukocyte antigen.
