Table 1 List of HLA Class I Luminex alleles based on binding activity of antibody 2E3.
From: Defining the structural basis for human leukocyte antigen reactivity in clinical transplantation
| Â | Definition | HLA Class I Luminex alleles |
|---|---|---|
Reactive alleles | 2E3 binds to these alleles at relatively low antibody concentrations No or insufficient structural evidence to suggest significantly disrupted interactions between 2E3 and these alleles | A*01:01, A*11:01, A*11:02, A*25:01, A*26:01, A*34:01, A*34:02, A*36:01, A*43:01, A*66:01, A*80:01, B*73:01, C*06:02, C*07:02, C*18:02 |
Cross-reactive alleles | 2E3 only binds to these alleles at high antibody concentrations Supported by structural analysis | A*02:01, A*02:03, A*02:06, A*03:01, A*23:01, A*24:02, A*24:03, A*29:01, A*29:02, A*31:01, A*32:01, A*33:01, A*33:03, A*66:02, A*68:01, A*68:02, A*69:01, A*74:01 |
Non-reactive alleles | 2E3 does not bind to these alleles even at high antibody concentrations Supported by structural analysis | A*30:01, A*30:02, B*07:02, B*08:01, B*13:01, B*13:02, B*14:01, B*14:02, B*15:01, B*15:02, B*15:03, B*15:10, B*15:11, B*15:12, B*15:13, B*15:16, B*18:01, B*27:05, B*27:08, B*35:01, B*37:01, B*38:01, B*39:01, B*40:01, B*40:02, B*40:06, B*41:01, B*42:01, B*44:02, B*44:03, B*45:01, B*46:01, B*47:01, B*48:01, B*49:01, B*50:01, B*51:01, B*51:02, B*52:01, B*53:01, B*54:01, B*55:01, B*56:01, B*57:01, B*57:03, B*58:01, B*59:01, B*67:01, B*78:01, B*81:01, B*82:01, C*01:02, C*02:02, C*03:02, C*03:03, C*03:04, C*04:01, C*05:01, C*08:01, C*12:03, C*14:02, C*15:02, C*16:01, C*17:01 |
