Table 1 Genes down-regulated in DDR1 silenced Hepatic Stellate Cells.
From: Silencing of sinusoidal DDR1 reduces murine liver metastasis by colon carcinoma
PANTHER GO-slim biological process | Upload_Genes (976) | (P value) |
|---|---|---|
Granulocyte chemotaxis (GO:0071621) | 19 | 8.79E−09 |
Leukocyte migration (GO:0050900) | 22 | 1.53E−09 |
Leukocyte chemotaxis (GO:0030595) | 19 | 6.89E−08 |
Positive regulation of GTPase activity (GO:0043547) | 9 | 1.48E−02 |
Inflammatory response (GO:0006954) | 33 | 7.79E−14 |
Defense response to virus (GO:0051607) | 10 | 1.26E−02 |
Cellular response to tumor necrosis factor (GO:0071356) | 9 | 3.81E−02 |
Positive regulation of ERK1 and ERK2 cascade (GO:0070374) | 10 | 1.58E−02 |
Cellular response to cytokine stimulus (GO:0071345) | 26 | 7.94E−08 |
Response to cytokine (GO:0034097) | 28 | 5.32E−08 |
Regulation of hydrolase activity (GO:0051336) | 17 | 6.66E−04 |
Cytokine-mediated signaling pathway (GO:0019221) | 21 | 3.78E−05 |
Cell migration (GO:0016477) | 35 | 9.21E−10 |
Response to lipopolysaccharide (GO:0032496) | 16 | 2.88E−03 |
Cellular response to lipopolysaccharide (GO:0071222) | 14 | 1.41E−02 |
Localization of cell (GO:0051674) | 35 | 5.01E−08 |
Cell motility (GO:0048870) | 35 | 5.01E−08 |
Response to organic substance (GO:0010033) | 40 | 6.38E−06 |
Divalent inorganic cation homeostasis (GO:0072507) | 22 | 3.94E−02 |
Regulation of catalytic activity (GO:0050790) | 26 | 7.82E−03 |
Defense response (GO:0006952) | 47 | 3.50E−06 |
MAPK cascade (GO:0000165) | 27 | 1.61E−02 |
Apoptotic process (GO:0006915) | 33 | 5.74E−03 |
Cell adhesion (GO:0007155) | 42 | 4.06E−04 |
Biological adhesion (GO:0022610) | 42 | 4.06E−04 |
Signal transduction by protein phosphorylation (GO:0023014) | 28 | 4.58E−02 |
Programmed cell death (GO:0012501) | 33 | 9.07E−03 |
Regulation of molecular function (GO:0065009) | 38 | 3.93E−03 |
Protein phosphorylation (GO:0006468) | 43 | 8.99E−04 |
Cell death (GO:0008219) | 33 | 2.62E−02 |
Response to stress (GO:0006950) | 53 | 1.95E−04 |
Immune system process (GO:0002376) | 88 | 5.44E−08 |
Response to chemical (GO:0042221) | 61 | 2.43E−04 |
Response to stimulus (GO:0050896) | 125 | 5.10E−11 |
Cellular protein metabolic process (GO:0044267) | 83 | 1.40E−03 |
Cellular macromolecule metabolic process (GO:0044260) | 83 | 1.47E−03 |
Intracellular signal transduction (GO:0035556) | 63 | 4.87E−02 |
Signal transduction (GO:0007165) | 127 | 3.92E−04 |
Cellular response to stimulus (GO:0051716) | 139 | 1.63E−03 |
