Table 5 Results of the gene to function pathway analysis.

From: Genetic and non-genetic factors associated with the phenotype of exceptional longevity & normal cognition

Category

GeneSet

N Genes

N Overlap

P

adjP

Genes

Link

Immunologic signatures

GSE12392_WT_VS_IFNB_KO _CD8A_POS_SPLEEN_DC_DN

200

4

\(4.59\times 10^{-6}\)

0.022

RYR3:PHB:GRIK2:ESR1

Link1

Transcription factor targets

AACTTT_UNKNOWN

1928

7

\(6.09 \times 10^{-5}\)

0.037

PBX1:RYR3:RBFOX1:DGKD: UBE2E1:CTNND2:ESR1

Link2

  1. Link 1: http://www.gsea-msigdb.org/gsea/msigdb/cards/GSE12392_WT_VS_IFNB_KO_CD8A_POS_SPLEEN_DC_DN
  2. Link 2: http://www.gsea-msigdb.org/gsea/msigdb/cards/AACTTT_UNKNOWN
  3. “adjP” refers to adjustment for multiple comparisons.
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