Table 1 Patient demographics: development and validation sets.
Development set | Validation set | Missing (%) | |
|---|---|---|---|
Date of transplant | 01/01/2007–05/31/2012 | 06/01/2012–12/31/2012 | |
n | 55,044 | 6176 | |
Recipient characteristics | |||
Age, mean (SD) | 52.76 (13.02) | 53.25 (13.19) | 0 |
Male, n (%) | 33,411 (60.7) | 3735 (60.5) | 0 |
Ethnicity, n (%) | 0 | ||
White | 25,081 (45.6) | 2724 (44.1) | |
Asian | 3300 (6.0) | 420 (6.8) | |
Black | 17,669 (32.1) | 1963 (31.8) | |
Hispanic | 7978 (14.5) | 970 (15.7) | |
Other | 1016 (1.8) | 97 (1.6) | |
BMI, mean (SD) | 28.06 (5.47) | 28.44 (5.49) | 0.2 |
Primary diagnosis, n (%) | 0.5 | ||
Diabetes | 14,632 (26.7) | 1694 (27.5) | |
Hypertension | 13,424 (24.5) | 1453 (23.6) | |
Other | 26,728 (48.8) | 3007 (48.9) | |
Pretransplant dialysis, n (%) | 48,444 (88.5) | 5500 (89.2) | 0.5 |
Serum creatinine, mean (SD) | 7.97 (3.50) | 7.97 (3.62) | 1 |
Initial waitlist status other than active, n (%) | 9647 (17.5) | 1400 (22.7) | 0 |
Diabetes, n (%) | 1 | ||
No | 35,141 (64.5) | 3961 (64.4) | |
Type I | 2680 (4.9) | 220 (3.6) | |
Type II | 14,276 (26.2) | 1830 (29.8) | |
Type other | 223 (0.4) | 34 (0.6) | |
T ype unknown | 2143 (3.9) | 103 (1.7) | |
Days on waiting list, mean (SD) | 858.52 (725.47) | 962.87 (774.94) | 0.1 |
Donor characteristics | |||
Age, mean (SD) | 38.77 (16.45) | 38.18 (16.13) | 0 |
DCD donor, n (%) | 7352 (13.4) | 944 (15.3) | 0 |
BUN, mean (SD) | 16.20 (10.76) | 17.27 (13.19) | 0.1 |
Terminal serum creatinine, mean (SD) | 1.14 (0.91) | 1.13 (0.92) | 0 |
BMI, mean (SD) | 27.24 (6.66) | 27.56 (6.85) | 0.1 |
History of hypertension, n (%) | 15,414 (28.2) | 1747 (28.5) | 0.6 |
Cause of death, n (%) | 0 | ||
Anoxia | 13,075 (23.8) | 1816 (29.4) | |
Cerebrovascular/stroke | 19,614 (35.6) | 1939 (31.4) | |
Head trauma | 20,579 (37.4) | 2242 (36.3) | |
Other | 1776 (3.2) | 177 (2.9) | |
ECD donor, n (%) | 9515 (17.3) | 911 (14.8) | 0 |
Mechanism of death, n (%) | 0 | ||
Cardiovascular | 6462 (11.7) | 838 (13.6) | |
Intracranial hemorrhage/stroke | 20,334 (36.9) | 2003 (32.4) | |
Gunshot wound | 5596 (10.2) | 622 (10.1) | |
Blunt injury | 13,901 (25.3) | 1562 (25.3) | |
Other | 8751 (15.9) | 1149 (18.6) | |
History of diabetes, n (%) | 0.5 | ||
No | 50,759 (92.7) | 5663 (92.2) | |
Type I | 2045 (3.7) | 226 (3.7) | |
Type II | 757 (1.4) | 96 (1.6) | |
Type other | 765 (1.4) | 107 (1.7) | |
Type unknown | 455 (0.8) | 49 (0.8) | |
Arginine vasopressin, n (%) | 30,988 (56.4) | 3564 (57.8) | 0.1 |
Steroids, n (%) | 38,715 (70.5) | 4219 (68.3) | 0.2 |
SGPT, mean (SD) | 107.35 (346.29) | 107.73 (293.77) | 0.5 |
Transplant characteristics | |||
Delayed graft function, n (%) | 13,792 (25.1) | 1624 (26.3) | 0 |
Allocation type, n (%) | 0 | ||
Local | 41,344 (75.1) | 4837 (78.3) | |
Regional | 4833 (8.8) | 550 (8.9) | |
National | 8867 (16.1) | 787 (12.7) | |
Cold ischemia time, mean (SD) | 17.73 (9.65) | 17.14 (8.64) | 2.9 |
Right kidney biopsy at recovery, n (%) | 24,659 (44.8) | 2929 (47.5) | 0.1 |
Left kidney biopsy at recovery, n (%) | 24,370 (44.3) | 2907 (47.1) | 0 |
Kidney pump, n (%) | 22,378 (40.7) | 2801 (45.4) | 0 |