Table 1 Patient demographics: development and validation sets.

From: Personalized prediction of delayed graft function for recipients of deceased donor kidney transplants with machine learning

 

Development set

Validation set

Missing (%)

Date of transplant

01/01/2007–05/31/2012

06/01/2012–12/31/2012

 

n

55,044

6176

 

Recipient characteristics

Age, mean (SD)

52.76 (13.02)

53.25 (13.19)

0

Male, n (%)

33,411 (60.7)

3735 (60.5)

0

Ethnicity, n (%)

0

 White

25,081 (45.6)

2724 (44.1)

 

 Asian

3300 (6.0)

420 (6.8)

 

 Black

17,669 (32.1)

1963 (31.8)

 

 Hispanic

7978 (14.5)

970 (15.7)

 

 Other

1016 (1.8)

97 (1.6)

 

BMI, mean (SD)

28.06 (5.47)

28.44 (5.49)

0.2

Primary diagnosis, n (%)

0.5

 Diabetes

14,632 (26.7)

1694 (27.5)

 

 Hypertension

13,424 (24.5)

1453 (23.6)

 

 Other

26,728 (48.8)

3007 (48.9)

 

Pretransplant dialysis, n (%)

48,444 (88.5)

5500 (89.2)

0.5

Serum creatinine, mean (SD)

7.97 (3.50)

7.97 (3.62)

1

Initial waitlist status other than active, n (%)

9647 (17.5)

1400 (22.7)

0

Diabetes, n (%)

1

 No

35,141 (64.5)

3961 (64.4)

 

 Type I

2680 (4.9)

220 (3.6)

 

 Type II

14,276 (26.2)

1830 (29.8)

 

 Type other

223 (0.4)

34 (0.6)

 

T ype unknown

2143 (3.9)

103 (1.7)

 

Days on waiting list, mean (SD)

858.52 (725.47)

962.87 (774.94)

0.1

Donor characteristics

Age, mean (SD)

38.77 (16.45)

38.18 (16.13)

0

DCD donor, n (%)

7352 (13.4)

944 (15.3)

0

BUN, mean (SD)

16.20 (10.76)

17.27 (13.19)

0.1

Terminal serum creatinine, mean (SD)

1.14 (0.91)

1.13 (0.92)

0

BMI, mean (SD)

27.24 (6.66)

27.56 (6.85)

0.1

History of hypertension, n (%)

15,414 (28.2)

1747 (28.5)

0.6

Cause of death, n (%)

0

 Anoxia

13,075 (23.8)

1816 (29.4)

 

 Cerebrovascular/stroke

19,614 (35.6)

1939 (31.4)

 

 Head trauma

20,579 (37.4)

2242 (36.3)

 

 Other

1776 (3.2)

177 (2.9)

 

ECD donor, n (%)

9515 (17.3)

911 (14.8)

0

Mechanism of death, n (%)

0

 Cardiovascular

6462 (11.7)

838 (13.6)

 

 Intracranial hemorrhage/stroke

20,334 (36.9)

2003 (32.4)

 

 Gunshot wound

5596 (10.2)

622 (10.1)

 

 Blunt injury

13,901 (25.3)

1562 (25.3)

 

 Other

8751 (15.9)

1149 (18.6)

 

History of diabetes, n (%)

0.5

 No

50,759 (92.7)

5663 (92.2)

 

 Type I

2045 (3.7)

226 (3.7)

 

 Type II

757 (1.4)

96 (1.6)

 

 Type other

765 (1.4)

107 (1.7)

 

 Type unknown

455 (0.8)

49 (0.8)

 

Arginine vasopressin, n (%)

30,988 (56.4)

3564 (57.8)

0.1

Steroids, n (%)

38,715 (70.5)

4219 (68.3)

0.2

SGPT, mean (SD)

107.35 (346.29)

107.73 (293.77)

0.5

Transplant characteristics

Delayed graft function, n (%)

13,792 (25.1)

1624 (26.3)

0

Allocation type, n (%)

  

0

 Local

41,344 (75.1)

4837 (78.3)

 

 Regional

4833 (8.8)

550 (8.9)

 

 National

8867 (16.1)

787 (12.7)

 

Cold ischemia time, mean (SD)

17.73 (9.65)

17.14 (8.64)

2.9

Right kidney biopsy at recovery, n (%)

24,659 (44.8)

2929 (47.5)

0.1

Left kidney biopsy at recovery, n (%)

24,370 (44.3)

2907 (47.1)

0

Kidney pump, n (%)

22,378 (40.7)

2801 (45.4)

0

  1. SD standard deviation, BMI Body Mass Index, DCD donation after cardiac death, BUN blood urea nitrogen, ECD expanded-criteria donation, SGPT serum glutamic pyruvic transaminase.