Table 1 Phenotypes.
Phenotype | Abbreviation | n | Min | Max | Mean | SD |
|---|---|---|---|---|---|---|
Endophenotypes | ||||||
Intermediates in cholesterol biosynthesis | ||||||
Squalene | Sq | 245 | 0.70 | 17.30 | 4.96 | 3.69 |
Lanosterol | Lan | 284 | 1.43 | 5.89 | 3.42 | 0.91 |
Lathosterol | Lat | 299 | 13.06 | 96.99 | 49.85 | 17.15 |
Desmosterol | Des | 300 | 22.33 | 123.63 | 68.35 | 20.06 |
Sum of intermediates | Sint | 300 | 36.15 | 222.51 | 129.05 | 35.00 |
Phytosterols | ||||||
Betasitosterol | Bsit | 297 | 45.36 | 470.17 | 186.60 | 96.30 |
Campesterol | Cste | 288 | 106.68 | 862.77 | 392.42 | 158.37 |
Stigmasterol | Stig | 249 | 0.16 | 2.56 | 1.14 | 0.48 |
Sum of phytosterols | Sphy | 290 | 187.96 | 1253.79 | 577.60 | 232.74 |
Microbiota-derived sterols | ||||||
Coprostanol | Csta | 298 | 1.95 | 31.12 | 13.66 | 6.35 |
Epicoprostanol | Esta | 276 | 0.23 | 5.41 | 2.23 | 1.11 |
Sum of microbiota-derived sterols | Sste | 303 | 2.17 | 35.01 | 15.84 | 7.28 |
End-point phenotypes | ||||||
LDL-Cholesterol | LDL-C | 296 | 30.82 | 86.53 | 57.70 | 10.67 |
HDL-Cholesterol | HDL-C | 317 | 13.00 | 57.00 | 36.19 | 7.92 |
Total Cholesterol | TC | 297 | 67.78 | 137.84 | 100.88 | 13.88 |
Triglycerides | TG | 295 | 42.57 | 200.12 | 119.68 | 31.02 |
