Table 1 Frequency and absolute number of the HLA-G 3′UTR alleles observed in patients with AIDS exhibiting CMV retinitis (CMV-R: Group I) and in patients with AIDS without CMV-R (Group II).
HLA-G position | Allele | Group I (N = 40) | Group II (N = 147) | Odds ratio | Etiologic fraction | P value |
|---|---|---|---|---|---|---|
+ 2960 (14 bp) | Ins | 0.3750 (30) | 0.3741 (110) | |||
Del | 0.6250 (50) | 0.6259 (184) | ||||
+ 3001C/T | C | 0.9750 (78) | 1.0000 (292) | |||
T | 0.0250 (2) | 0.0000 (0) | 18.631 (95% CI 0.885–392.043) | 0.024 | 0.046 | |
+ 3003C/T | C | 0.1625 (13) | 0.1054 (31) | |||
T | 0.8375 (67) | 0.8946 (263) | ||||
+ 3010C/G | C | 0.4625 (37) | 0.5510 (162) | |||
G | 0.5375 (43) | 0.4490 (132) | ||||
+ 3027C/A | C | 0.9750 (78) | 0.9524 (280) | |||
A | 0.0250 (2) | 0.0476 (14) | ||||
+ 3032C/G | C | 0.0125 (1) | 0.0034 (1) | |||
G | 0.9875 (79) | 0.9966 (293) | ||||
+ 3035C/T | C | 0.8875 (71) | 0.8810 (259) | |||
T | 0.1125 (9) | 0.1190 (35) | ||||
+ 3142C/G | C | 0.5385 (42) | 0.4490 (132) | |||
G | 0.4615 (36) | 0.5510 (162) | ||||
+ 3187A/G | A | 0.7250 (58) | 0.6837 (201) | |||
G | 0.2750 (22) | 0.3163 (93) | ||||
+ 3196C/G | C | 0.7179 (56) | 0.7109 (209) | |||
G | 0.2821 (22) | 0.2891 (85) | ||||
+ 3227A/G | A | 0.0405 (3) | 0.0429 (6) | |||
G | 0.9595 (71) | 0.9571 (134) |
