Table 2 Frequency and absolute number of the HLA-G 3′UTR genotypes observed in patients with AIDS exhibiting CMV retinitis (CMV-R: Group I) and in patients with AIDS without CMV-R (Group II).
HLA-G position | Genotype | Group I (N = 40) | Group II (N = 147) | Odds ratio | Etiologic fraction | Preventive fraction | P value |
|---|---|---|---|---|---|---|---|
+ 2960 (14bp) | DD | 0.3750 (15) | 0.3946 (58) | ||||
DI | 0.5000 (20) | 0.4626 (68) | |||||
II | 0.1250 (5) | 0.1429 (21) | |||||
+ 3001C/T | CC | 0.9500(38) | 1.0000(146) | 0.053 (95% CI 0.002–1.117) | – | 0.945 | 0.045 |
CT | 0.0500 (2) | 0.0000 (0) | 19.026 (95% CI 0.895–404.579) | 0.047 | – | 0.045 | |
TT | 0.0000 (0) | 0.0000 (0) | |||||
+ 3003C/T | CC | 0.0250 (1) | 0.0068 (1) | ||||
CT | 0.2750 (11) | 0.1973 (29) | |||||
TT | 0.7000 (28) | 0.7959 (117) | |||||
+ 3010C/G | CC | 0.2000 (8) | 0.2857 (42) | ||||
CG | 0.5250 (21) | 0.5306 (78) | |||||
GG | 0.2750 (11) | 0.1837(27) | |||||
+ 3027C/A | AA | 0.0000 (0) | 0.0000 (0) | ||||
AC | 0.0500 (2) | 0.0952 (14) | |||||
CC | 0.9500 (38) | 0.9048 (133) | |||||
+ 3032C/G | CC | 0.0000 (0) | 0.0000 (0) | ||||
CG | 0.0250 (1) | 0.0068 (1) | |||||
GG | 0.9750 (39) | 0.9932 (146) | |||||
+ 3035C/T | CC | 0.7750 (31) | 0.7687 (113) | ||||
CT | 0.2250 (9) | 0.2245 (33) | |||||
TT | 0.0000 (0) | 0.0068 (1) | |||||
+ 3142C/G | CC | 0.2821(11) | 0.1837 (27) | ||||
CG | 0.5128 (20) | 0.5306 (78) | |||||
GG | 0.2051 (8) | 0.2857 (42) | |||||
+ 3187A/G | AA | 0.4750 (19) | 0.4354 (64) | ||||
AG | 0.5000 (20) | 0.4966 (73) | |||||
GG | 0.0250(1) | 0.0680 (10) | |||||
+ 3196C/G | CC | 0.4359 (17) | 0.4762 (70) | ||||
CG | 0.5641 (22) | 0.4694 (69) | |||||
GG | 0.0000 (0) | 0.0544 (8) | |||||
+ 3227A/G | AA | 0,0000 (0) | 0.0000 (0) | ||||
GA | 0.0811 (3) | 0.0857 (6) | |||||
GG | 0.9189 (43) | 0.9143 (64) |
