Table 3 Radiological and gasometric characteristics of patients hospitalized with COVID-19 pneumonia at admission.

From: Development and validation of a clinical score to estimate progression to severe or critical state in COVID-19 pneumonia hospitalized patients

 

All patients

Severe course

Odds ratio (95%CI)

p value

Missing

(n = 229)

Yes (n = 51)

No (n = 178)

Radiologic

0

     

Unilateral consolidation

 

98 (42.8)

12 (23.5)

86 (48.3)

Reference

Bilateral consolidation

 

81 (35.4)

28 (54.9)

53 (29.8)

3.7 (1.7, 8.1)

0.005

Bilateral interstitial abnormalities

 

26 (11.3)

5 (9.8)

21 (11.8)

1.7 (0.5, 5.4)

0.361

Bilateral consolidation + interstitial

 

24 (10.5)

6 (11.8)

18 (10.1)

2.4 (0.8, 7.2)

0.122

Gasometry

FiO2

21

0.21 (0.21, 0.21)

0.21 (0.21, 0.21)

0.21 (0.21, 0.21)

50 (0.2, 12,900)

0.166

pH

25

7.46 (7.13, 7.48)

7.47 (7.41, 7.49)

7.46 (7.43, 7.48)

0.57 (0.00, 680)

0.877

PaCO2, mm Hg

25

32.6 (29.4, 35.7)

31.3 (28.5, 36.0)

32.8 (30.0, 35.6)

0.97 (0.91, 1.03)

0.347

PaO2, mm Hg

25

67.1 (60.4, 75.6)

60.0 (51.8, 67.8)

69.7 (63.1, 76.5)

0.95 (0.93, 0.98)

 < 0.001

HCO3−, mmol/L

25

23.0 (21.0, 25.0)

22.2 (20.0, 24.1)

23.0 (21.0, 25.0)

0.92 (0.83, 1.02)

0.117

SaO2, %

23

94.0 (91.8, 95.2)

91.4 (86.0, 94.0)

94.0 (92.8, 95.4)

0.85 (0.79, 0.92)

 < 0.001

PaO2/FiO2 ratio, mm Hg

27

313 (271, 354)

262 (227, 300)

326 (290, 360)

0.99 (0.98, 0.99)

 < 0.001

SaO2/FiO2 ratio

24

444 (421, 452)

423 (383, 441)

447 (433, 452)

0.99 (0.99, 1.00)

0.001

  1. Data are n (%) or median (IQR). 95%CI, 95% Confidence Interval.
  2. Severe course was death from any cause, use of mechanic invasive ventilation, or intensive care unit stay.