Figure 3 | Scientific Reports

Figure 3

From: Increased expression of LCN2 formed a positive feedback loop with activation of the ERK pathway in human kidney cells during kidney stone formation

Figure 3

LCN2 affects the renal function. HK-2 (A) and HEK-293 (B) were transfected with pCDNA3.1 vector or LCN2, and the expressions of LCN2 and GAPDH were analyzed by western blot. HK-2 (C) and HEK-293 (D) were transfected with pCDNA3.1 vector or LCN2, and then examined the number of cells at each time point. HK-2 (E) and HEK-293 (F) were treated with rhLCN2, then examined the number of cells at each time point. All experiments were repeated at least three times. (*P < 0.05, **P < 0.01, ***P < 0.001).

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