Table 2 Body-weight (g) measurement in CD2F1 mice after IL-18BP or vehicle treatment.
From: IL-18 binding protein (IL-18BP) as a novel radiation countermeasure after radiation exposure in mice
Treatment | Pre-injection | D1 | D2 | D3 | D4 | D7 | D9 | D11 | D14 |
|---|---|---|---|---|---|---|---|---|---|
Vehicle | 28.7 ± 0.9 | 28.4 ± 1.0 | 28.3 ± 1.3 | 28.0 ± 1.0 | 28.3 ± 1.0 | 28.6 ± 0.7 | 28.8 ± 0.9 | 29.2 ± 1.0 | 28.8 ± 1.0 |
IL-18BP | |||||||||
0.25 mg/kg | 28.4 ± 3.8 | 28.1 ± 3.5 | 28.3 ± 3.7 | 28.4 ± 3.7 | 28.7 ± 3.8 | 29.1 ± 3.8 | 29.1 ± 4.0 | 29.9 ± 4.2 | 29.5 ± 4.2 |
0.5 mg/kg | 27.1 ± 1.3 | 26.7 ± 1.5 | 26.4 ± 1.3 | 26.5 ± 1.3 | 27.4 ± 1.3 | 27.5 ± 1.5 | 27.3 ± 1.6 | 28.0 ± 1.7 | 28.9 ± 1.7 |
1.0 mg/kg | 28.5 ± 1.8 | 28.4 ± 2.0 | 27.9 ± 2.0 | 27.9 ± 2.0 | 28.0 ± 2.0 | 28.2 ± 1.8 | 28.6 ± 1.9 | 28.6 ± 1.9 | 28.7 ± 1.8 |
1.5 mg/kg | 28.4 ± 2.0 | 28.0 ± 2.1 | 28.0 ± 2.0 | 28.1 ± 1.7 | 28.5 ± 1.9 | 28.6 ± 1.6 | 28.7 ± 1.6 | 29.0 ± 1.5 | 29.0 ± 1.4 |
2.0 mg/kg | 29.2 ± 1.6 | 29.2 ± 1.6 | 29.0 ± 1.6 | 29.0 ± 1.8 | 29.5 ± 1.8 | 29.6 ± 2.0 | 29.7 ± 2.1 | 30.1 ± 2.1 | 29.9 ± 2.2 |
3.0 mg/kg | 29.1 ± 1.3 | 29.3 ± 1.5 | 28.9 ± 1.4 | 28.5 ± 1.4 | 29.3 ± 0.7 | 28.5 ± 1.4 | 28.9 ± 1.6 | 29.1 ± 1.5 | 29.2 ± 1.8 |
5.0 mg/kg | 29.2 ± 1.6 | 29.0 ± 1.8 | 28.8 ± 1.7 | 28.5 ± 1.8 | 29.2 ± 1.2 | 28.5 ± 1.7 | 28.8 ± 1.7 | 29.2 ± 1.6 | 29.3 ± 1.8 |
