Table 3 Blood cell counts in CD2F1 mice 14 days after IL-18BP or vehicle treatment.
From: IL-18 binding protein (IL-18BP) as a novel radiation countermeasure after radiation exposure in mice
Treatment | WBC (× 103) | NEU (× 103) | LYM (× 103) | MONO (× 103) | RBC (× 103) | HGB (g/dL) | PLT (× 103) |
|---|---|---|---|---|---|---|---|
Vehicle | 6.55 ± 2.37 | 1.54 ± 0.66 | 4.34 ± 1.55 | 0.16 ± 0.08 | 8.82 ± 1.70 | 12.78 ± 2.94 | 1001.00 ± 217.74 |
IL-18BP | |||||||
0.25 mg/kg | 4.83 ± 0.71 | 1.04 ± 0.16 | 3.38 ± 0.60 | 0.09 ± 0.06 | 9.22 ± 0.48 | 13.07 ± 0.56 | 1055.67 ± 81.99 |
0.5 mg/kg | 4.36 ± 1.73 | 0.98 ± 0.13 | 3.55 ± 1.67 | 0.05 ± 0.04 | 7.91 ± 2.50 | 10.20 ± 3.65 * | 921.67 ± 382.38 |
1.0 mg/kg | 6.51 ± 1.24 | 1.45 ± 0.43 | 4.62 ± 0.84 | 0.17 ± 0.09 | 8.93 ± 0.56 | 13.40 ± 0.95 | 960.17 ± 142.65 |
1.5 mg/kg | 6.32 ± 1.63 | 1.02 ± 0.53 | 4.74 ± 1.07 | 0.14 ± 0.09 | 8.60 ± 0.59 | 13.07 ± 0.76 | 1075.33 ± 114.34 |
2.0 mg/kg | 3.99 ± 1.09 * | 0.64 ± 0.20 * | 3.60 ± 0.86 | 0.11 ± 0.05 | 7.77 ± 2.18 | 11.85 ± 3.28 | 775.17 ± 267.59 |
3.0 mg/kg | 5.55 ± 1.32 | 1.26 ± 0.41 | 3.89 ± 0.88 | 0.15 ± 0.02 | 9.35 ± 0.37 | 14.20 ± 0.3 | 1008.00 ± 76.28 |
5.0 mg/kg | 7.99 ± 0.63 | 1.54 ± 0.30 | 5.88 ± 0.44 | 0.23 ± 0.12 | 9.59 ± 0.38 | 14.43 ± 0.55 | 1010.33 ± 179.73 |
