Table 2 The area under the curve (AUC), sensitivity and specificity values of DE-miRNAs.

From: miRNA profiles of canine cutaneous mast cell tumours with early nodal metastasis and evaluation as potential biomarkers

 

miRNA

AUC

95% CI

P-value

Cut-off

Sensitivity

1-Specificity

Downregulated

miR-885

0.9181

0.8276–1.000

 < 0.0001

0.0357

0.8889

0.9474

miR-92a

0.7427

0.5925–0.8929

 = 0.0015

0.814

0.7222

0.6842

miR-338

0.7339

0.5827–0.8851

 = 0.0024

1.7878

0.6111

0.7895

Upregulated

miR-21

0.9825

0.9825–0.9825

 < 0.0001

1.6250

0.9444

0.9474

miR-379

0.9211

0.8328–1.000

 < 0.0001

11.5688

1.000

0.7895

W-AV*

miR-379 + miR-21 + miR-885

0.9854

0.9854–0.9854

 < 0.0001

0.1654

1.000

0.9444

W-AV-HN**

miR-379 + miR-21 + miR-885

0.8923

0.759–1.000

 < 0.0001

0.5528

0.9231

0.8000

  1. *W-AV = weighted average relative quantification of miR-379 + miR-21 + miR-885 in healthy versus MCT samples.
  2. **W-AV-HN = weighted average relative quantification of miR-379 + miR-21 + miR-885 in HN0/1 versus HN2 samples.
Back to article page