Table 1 Demographic and clinical characteristics of 15 patients from 14 families with retinitis pigmentosa associated with PDE6B variants; visual and retinal parameters were assessed at the time of genetic testing.

Family no.	Subject no.	Age, years	Sex	Follow-up duration, years	BCVA, LogMAR		First symptom		Age at diagnosis, years	Family history	Visual field	OCT parameters
Family no.	Subject no.	Age, years	Sex	Follow-up duration, years	OD	OS	Age at onset, years	Chief complaint	Age at diagnosis, years	Family history	Visual field	IS/OS, μm	CRT, μm	ONLT, μm	ERM	CME
1	1-III-1	14	M	3	0.00	0.00	7	Night blindness	11	No	PRS	3654	253	70	No	Yes
2	2-III-2	26	F	2	0.40	0.15	10	Dyschromatopsia	11	No	PRS	2420	248	90	Yes	Yes
3	3-III-1	13	F	1	0.40	0.20	4	Decreased VA	12	No	Center < 20°	1719	306	94	No	Yes
4	4-II-3	67	M	2	3.00	0.50	10	Night blindness	20	Yes	TVFD (OD)	473	315	21	Yes	No^a
											PP (OS)
5	5-III-1	17	F	1	0.15	0.00	15	Night blindness	16	Yes	center < 30°	4658	261	97	No	No
5	5-III-2	15	M	1	0.10	0.10	14	Night blindness	14	Yes	center < 30°	3889	273	89	No	No
6	6-II-3	40	F	4	0.00	0.00	30	Night blindness	40	No	N/A	2644	271	62	No	No
7	7-II-5	55	M	1	0.40	0.40	47	Night blindness	55	No	PRS	1495	235	62	Yes	Yes
8	8-II-2	33	F	1	0.00	0.40	14	Night blindness	33	Yes	PRS	4046	284	72	No	Yes
9	9-II-3	62	M	1	3.00	0.50	10	Night blindness	20	Yes	TVFD (OD)	328	195	N/A	Yes	No^a
											PP (OS)
10	10-II-3	50	M	3	3.00	3.00	5	Night blindness	24	No	PP	394	217	N/A	Yes	No^a
11	11-II-5	38	M	6	0.40	0.40	10	Night blindness	21	Yes	Center < 15°	1401	230	31	Yes	Yes
12	12-II-1	44	F	12	0.40	1.00	7	Night blindness	31	No	Center < 10°	812	189	38	Yes	No
13	13-II-5	67	F	6	0.10	0.10	42	Night blindness	60	No	Center < 10°	4715	252	56	Yes	No
14	14-II-5	56	F	2	1.30	0.40	6	Night blindness	44	No	PP	803	257	35	No	Yes^a
Median		40.0		2.0	0.40	0.40	10.0		21.0			1719.0	253.0	62.0
Mean		39.8		3.1	0.84	0.48	15.4		27.5			2230.1	252.4	62.2

BCVA best-corrected visual acuity; LogMAR logarithm of the minimum angle of resolution; OCT optical coherence tomography; IS/OS width of the inner segment/outer segment band; CRT central retinal thickness; ONLT outer nuclear layer thickness; ERM epiretinal membrane; CME cystoid macular edema; PRS paracentral ring scotoma; TVFD total visual field defect; PP pinpoint visual field; N/A not available; VA visual acuity; OD oculus dexter; OS oculus sinister.
^aThe patients who were excluded from calculating the incidence of cystoid macular edema due to diffuse foveal atrophy accompanied by residual visual field less than five degree.

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