Figure 4
From: Singular manifolds of proteomic drivers to model the evolution of inflammatory bowel disease status
Representative repertoire of graphs by enriched functions that are well preserved in UC. (A) Immune response. (B) Inflammatory response. (C) Innate immune response. The protein interaction graphs were constructed using Genemania17. Edge colouring in graphs: purple stands for Co-expression, orange for Predicted, light-blue for Pathway, light-red for Physical interactions, green for Shared protein domains and blue for Co-localisation. Boxplots of expression for the most attractive drivers respect to UC status are indicated by red circles at the top of each subgraph. Initial P upon the boxplot title amount to p-value associated with the IBD status correlation, whereas PC are the initials to positive control, i.e., proteins already described as IBD-related. For the sake of simplicity, we highlighted some candidates simply by its identifiers. See Fig. S0 for more details on networks.
