Table 1 Baseline characteristics of recipients and donors according to the microbial distance groups.
Variables | Most similar (1st tertile) | Similar (2nd tertile) | Dissimilar (3rd tertile) | P |
|---|---|---|---|---|
N = 20 | N = 23 | N = 24 | ||
Recipient | ||||
Age (years) | 49.5 ± 10.6 | 47.9 ± 13.6 | 46.4 ± 14.6 | 0.871 |
Male gender (%) | 17 (85.0) | 12 (52.2) | 9 (37.5) | 0.006 |
BMI (kg/m2) | 23.9 ± 2.5 | 22.8 ± 4.0 | 22.3 ± 5.0 | 0.227 |
DM (%) | 10 (50.0) | 7 (30.4) | 3 (12.5) | 0.026 |
HTN (%) | 17 (85.0) | 17 (73.9) | 16 (66.7) | 0.378 |
Cause of end-stage renal disease | 0.247 | |||
DM | 8 (40.0) | 5 (21.7) | 3 (12.5) | |
HTN | 0 (0) | 1 (4.3) | 0 (0) | |
Glomerulonephritis | 6 (30.0) | 8 (34.8) | 7 (29.2) | |
Polycystic kidney disease | 3 (15.0) | 2 (8.7) | 2 (8.3) | |
Unknown | 3 (15.0) | 7 (30.4) | 12 (50.0) | |
Dialysis duration (months) | 7.4 ± 14.4 | 12.1 ± 16.4 | 13.3 ± 32.4 | 0.163 |
ABO incompatibility (%) | 6 (30.0) | 5 (21.7) | 7 (29.2) | 0.790 |
HLA incompatibility (%) | 1 (5.0) | 3 (13.0) | 1 (12.5) | 0.635 |
Number of HLA mismatch | 3.6 ± 1.8 | 3.4 ± 1.8 | 2.5 ± 1.6 | 0.061 |
Donor type (%) | 0.048 | |||
Related | 6 (30.0) | 9 (39.1) | 15 (62.5) | |
Unrelated (Spouse + others) | 14 (70.0) | 14 (60.9) | 9 (37.5) | |
Spouse | 12 (60.0) | 14 (60.9) | 6 (25.0) | |
Others | 2 (10.0) | 0 (0) | 3 (12.5) | |
Donor | ||||
Age (years) | 46.2 ± 10.7 | 51.6 ± 7.9 | 45.8 ± 13.2 | 0.228 |
Male gender (%) | 7 (35.0) | 9 (39.1) | 11 (45.8) | 0.759 |
BMI (kg/m2) | 24.3 ± 3.3 | 24.6 ± 3.5 | 23.4 ± 2.9 | 0.541 |
Weighted UniFrac distance | 0.29 ± 0.04 | 0.43 ± 0.04 | 0.59 ± 0.07 | < 0.001 |
