Figure 5
From: The bone marrow microenvironment of pre-B acute lymphoblastic leukemia at single-cell resolution
B-ALL alters the HSPC compartment in the bone marrow of leukemia-bearing mice. (a) Percentage (left) and number (right) of lineage negative (lin−) cells. (b) Percentage of LSK cells and myeloid progenitors. (c) Percentage of HSCs. (d) Percentage of multipotent progenitors. (e) Percentage of CMPs, GMPs, MEPs and CLPs. (f) Red blood cell count, hemoglobin, hematocrit and platelet count in the peripheral blood of leukemia-bearing mice (n = 3–8). (a–e) n = 5–7. Throughout, *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001. Error bars represent mean ± SEM.
