Table 2 Demographic and clinical variable summary of PD discovery (PPMI) and validation (AETIONOMY PD, DIGIPD, ICEBERG) cohorts.

From: Clustering of Alzheimer’s and Parkinson’s disease based on genetic burden of shared molecular mechanisms

Cohort

Age

Gender (m/f)

UPDRS1

UPDRS2

UPDRS3 off

UPDRS3 on

MOCA

HADS anxiety

Schwab-England

PPMI

62.5 (14.14)

238/120

5 (5)

5 (6)

19 (11.75)

NA

28 (3)

NA

NA

AETIONOMY PD

64 (11.25)

59/29

7 (6.75)

7 (8.75)

28 (17)

0 (0)

27 (4)

5 (5)

2 (0)

DIGPD

61 (12)

100/73

7 (6)

5 (5)

21 (11)

0 (0)

NA

6 (4)

2 (1)

ICEBERG

67 (16.5)

30/12

10 (4)

7 (6)

29.5 (11.5)

0 (0)

27 (3)

7 (3)

2 (0)

  1. The data shows only de novo diagnosed idiopathic PD cases. The Table shows the median of each variable and the inter-quartile range (IQR) in brackets.