Table 3 Parameters of BCAA- and phosphate-fed rats.

From: Dietary casein, egg albumin, and branched-chain amino acids attenuate phosphate-induced renal tubulointerstitial injury in rats

Parameters

Group

HPi + BCAA_0

Group

HPi + BCAA_10

Urine (2 w)

Phosphate (mg/6 h)

17.2 ± 9.1Ref

15.3 ± 6.3NS

Calcium (mg/6 h) (× 10–1 mg/6 h)

0.61 ± 0.26Ref

0.74 ± 0.19NS

Stool (2 w)

Phosphate (mg/6 h)

43.3 ± 2.4Ref

39.8 ± 5.1NS

Calcium (mg/6 h)

32.8 ± 9.0Ref

37.3 ± 6.7NS

Serum (6 w)

Creatinine (mg/dl)

1.08 ± 0.37Ref

0.73 ± 0.16*

Urea nitrogen (mg/dl)

30.6 ± 10.1Ref

39.3 ± 5.1NS

Phosphate (mg/dl)

14.3 ± 4.24Ref

8.2 ± 1.2**

Calcium (mg/dl)

7.9 ± 0.4Ref

8.6 ± 1.1NS

Plasma (6 w)

iFGF23 (pg/ml)

(× 103 pg/ml)

4.0 ± 1.4Ref

0.87 ± 0.50***

iPTH (pg/ml)

1936.7 ± 797.0Ref

700.8 ± 177.2**

  1. Parameters of the rats shown in Figs. 5 and 6 are summarized. Urine and stool samples were collected at 2 weeks after the initiation of dietary intervention. Serum and plasma samples were collected at the time of dissection. All results are presented as means ± SD. Statistical analysis was performed by the unpaired t-test.
  2. Abbreviations: iFGF23, intact fibroblast growth factor 23; iPTH, intact parathyroid hormone; Ref, reference; NS, not significant; SD, standard deviation; w, week (N = 4–9 in each group; *P < 0.05, **P < 0.01, ***P < 0.001, unpaired t-test).
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