Table 2 Cytotoxicity values (CC50), minimum inhibitory concentration (MIC) and selective index (SI) of the N, O acetals derived from 2-amino-1,4-naphthoquinone.

From: Antibiofilm effects of N,O-acetals derived from 2-amino-1,4-naphthoquinone are associated with downregulation of important global virulence regulators in methicillin-resistant Staphylococcus aureus

Derivative

CC50 (µg/mL)

MIC (µg/mL)

SI

6a

97.35 ± 3.12

128

0.76

7a

155.28 ± 1.03

256

0.61

7b

219.95 ± 1.87

128

1.72

7c

20.15 ± 2.11

64

0.31

TET

66.6 ± 2.22

32

2.08

TMP-STX

32.58 ± 1.33

32

1.01

  1. TET tetracycline, TMP-STX trimethoprim-sulfamethoxazole.
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