Table 1 Advanced spray drying parameters for co-spray dried (co-SD) powders from methanol (MeOH) solution using organic solution advanced closed mode spray drying particle engineering design.

From: Design and development of innovative microparticulate/nanoparticulate inhalable dry powders of a novel synthetic trifluorinated chalcone derivative and Nrf2 agonist

Powder composition (molar ratio)

Molar ratio composition (TMC:Man)

Feed concentration in MeOH (% w/v)

Pump rate (%)

Inlet T (°C)

Outlet T (°C)

Co-SD TMC:Man

25:75

0.156

25

89–90

50–51

Co-SD TMC:Man

25:75

0.156

50*

90

40–44

Co-SD TMC:Man

25:75

0.156

75

90

29–36

Co-SD TMC:Man

25:75

0.156

100

90–91

18–23

  1. *Not used for further experiments due to insufficient mass.