Figure 4

BAFF treatment of EBV-infected LCL leads to increased EBV replication and cell expansion. LCL B cells from four different renal transplant patients were cultured with increasing BAFF concentrations (x-axis), with MPA + Tac (black symbols), or without MPA + Tac (red symbols). EBV load under BAFF treatment was assessed by normalization of EBV-PCR data obtained after BAFF treatment to untreated samples (a). The normalized LCL B cell count (b) represents the ratio of the B cell count by the untreated (BAFF = 0 and No IS) LCL B cells.