Figure 3
Breast cancer stem cells markers (ALDH+) correlated with BCRP expression in triple negative patients. Correlation of BCRP protein and ABCG2 gene expression with BCSC markers (ALDH+ and CD24-CD44 + CD49f + EPCAM +) in breast cancer patients who received or not NAT before surgery. (a) Correlation of BCRP protein with ALDH + and CD24-CD44 + CD49f+ EPCAM + expression in all samples. (b) Correlation of ABCG2 gene expression with ALDH + and CD24-CD44 + CD49f + EPCAM + in all samples. (c) Correlation of BCRP with ALDH + and CD24-CD44 + CD49f + EPCAM + expression in breast cancer patients who received NAT before surgery. Correlation of BCRP protein with BCSC markers (ALDH+ and CD24-CD44+ CD49f + EPCAM+) expression in (d) LA only, (e) LB only and (f) TN patients who received NAT before surgery. Correlations were assessed using nonparametric Spearman correlation, determination coefficient r and p-value are shown. *p < 0.05.
