Table 1 Clinicopathologic features of this cohort.

From: Comprehensive genomic profile of Chinese lung cancer patients and mutation characteristics of individuals resistant to icotinib/gefitinib

Total

371

Gender (n/%)

Male

187 (50.40%)

Female

184 (49.60%)

Age

Median (range)

62 (27–84)

Smoking status (n/%)

Smoking

70 (18.87%)

Nonsmoking

110 (29.65%)

Unknown

191 (51.48%)

TMB

Median (range)

3 (0–55.7)

Tumor sites (n/%)

Primary lesion

297 (80.05%)

Metastases lesion

56 (15.09%)

Pleural

26 (7.0%)

Lymphatic

9 (2.43%)

Bone

9 (2.43%)

Liver

3 (0.81%)

brain

2 (0.54%)

peritoneal

2 (0.54%)

Adrenal gland

1 (0.27%)

Unclear

4 (1.08%)

Unknown

18 (4.85%)

Tumor stage (n/%)

I

42 (11.32%)

II

30 (8.09%)

III

46 (12.40%)

IV

121 (32.61%)

Unknown

132 (35.58%)

Tumor subtype (n/%)

Non-small cell lung cancer

335 (90.30%)

Lung adenocarcinoma

286

Lung squamous cell carcinoma

30

Lung adenosquamous carcinoma

8

Unknown

11

Small cell lung cancer

11 (2.97%)

Unknown

25 (6.74%)

  1. TMB tumor mutational burden.