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Figure 2

From: Western diet, obesity and bariatric surgery sequentially modulated anxiety, eating patterns and brain responses to sucrose in adult Yucatan minipigs

Figure 2

Study 1. (a) Holebard discrimination task results. Comparisons between lean SD (white) and lean WD (light grey) for Working memory scores, Number of bowl visits (occurences), and Walls exploration time (s). With *P < 0.05, **P < 0.01, ***P < 0.001. (b) Two-choice feed test results. Comparisons between lean SD (white) and lean WD (light grey), for High-sucrose feed intake (g) and “Bite” frequency for HS food (occurences/min). (c) Horizontal brain maps (whole-brain analyses) of higher glucose metabolism in response to sucrose in WD compared to SD lean animals (P < 0.001, uncorrected); DV, dorsal–ventral position in mm related to the posterior commissure. (d) Brain areas for which higher glucose metabolism was detected after a ROI (regions of interest) analysis based on a priori hypotheses. The contrasts and statistical thresholds (at the peak) are the same as those presented for the whole-brain analysis.

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