Figure 2 | Scientific Reports

Figure 2

From: Acute kidney injury risk in orthopaedic trauma patients pre and post surgery using a biomarker algorithm and clinical risk score

Figure 2

(A) Pre surgery serum biomarker predicted probabilities for AKI development post operatively. H-FABP, MK, sTNFR1 and sTNFR2 predicted probabilities for preoperative serum levels. Wilcoxon rank sum statistical significance is indicated by *p ≤ 0.05, **p ≤ 0.01, ****p ≤ 0.0001. AKI acute kidney injury, H-FABP heart-type fatty acid-binding protein, MK midkine, sTNFR soluble tumour necrosis factor receptor. (B) Receiver operator characteristics for pre surgery serum biomarkers. H-FABP (AUROC 0.712), MK (AUROC 0.615), sTNFR1 (AUROC 0.729) and sTNFR2 (AUROC 0.634). AUROC area under the receiver operator characteristic, H-FABP heart-type fatty acid-binding protein, MK midkine, sTNFR soluble tumour necrosis factor receptor.

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