Figure 3 | Scientific Reports

Figure 3

From: Galectin-3 gene deletion results in defective adipose tissue maturation and impaired insulin sensitivity and glucose homeostasis

Figure 3

Tissue and systemic inflammation in WT and Lgals3−/− mice aged 2 months. qRT-PCR analysis of the inflammatory markers Tnfa, Il1b, Il6, and Ccl2 in SAT and VAT (a); representative immunohistochemical staining for F4/80 (original magnification, 400X; black arrows = macrophages), and measurement of positive cell number in VAT (b); serum levels of IL-6 (c); and qRT-PCR analysis of the ER stress markers Hspa5, Ddit3, and Xbp1 in VAT (d) in WT and Lgals3−/− mice. Values represent the mean ± SD (n = 6 mice per genotype). White bars = WT mice; black bars = Lgals3−/− mice; *P < 0.05, **P < 0.01 or ***P < 0.001 versus WT.

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