Figure 5 | Scientific Reports

Figure 5

From: Galectin-3 gene deletion results in defective adipose tissue maturation and impaired insulin sensitivity and glucose homeostasis

Figure 5

AT phenotype and inflammation in 5-month-old WT and Lgals3−/− mice. Quantification of size, number, density and size distribution of adipocytes from VAT (a); adipocyte size from SAT (b); serum levels of leptin and adiponectin (c); qRT-PCR analysis of the inflammatory markers Tnfa, Il1b, Il6, and Ccl2 in SAT and VAT (d); representative immunohistochemical staining for F4/80 (original magnification, 400X; black arrows = macrophages), measurement of F4/80 positive cell number, and RT-PCR analysis of the macrophage marker Cd68 in VAT (e) in WT and Lgals3−/− mice. Values represent the mean ± SD (n = 6 per genotype). White bars = WT mice; black bars = Lgals3−/− mice; *P < 0.05, **P < 0.01 or ***P < 0.001 versus WT.

Back to article page