Figure 5
From: New insights into quetiapine metabolism using molecular networking
in vivo versus in vitro quetiapine metabolism. Blood sample from a patient treated with quetiapine was compared with differentiated HepaRG cells culture media incubated with quetiapine (13 µM) during H24. In this quetiapine-containing cluster, patient sample and differentiated HepaRG cells supernatant are depicted in blue and orange, respectively. Nodes are labelled with the exact protonated mass (m/z), chemical structures, and retention times and the links are labelled with the exact mass shift.
