Figure 7 | Scientific Reports

Figure 7

From: Corticotropin-releasing factor infusion in the bed nucleus of the stria terminalis of lactating mice alters maternal care and induces behavioural phenotypes in offspring

Figure 7

Parameters of the elevated plus-maze. (a) Time spent (in seconds) in the open arms by SAL and CRF offspring. (b) Number of entries into the open arms by SAL and CRF offspring. (c) Number of stretching behaviour by SAL and CRF offspring. (d) Time spent (in seconds) in the open arms by CT and LB offspring. (e) Number of entries into the open arms by CT and LB offspring. (f) Number of stretching behaviour by CT and LB offspring. Results are presented as means SEM. Two-way ANOVA, interaction-effect, where CRF males increased their time while CRF females decreased. *p < 0.05, 2-way ANOVA, treatment-effect. n = 10–12 animals per group. SAL, offspring of saline-infused dams; CRF, offspring of corticotropin-releasing factor-infused dams; CT, offspring of control dams; LB, offspring of stressed dams.

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