Table 3 Treatment-related adverse events.

From: First-line axitinib therapy is less effective in metastatic renal cell carcinoma with spindle histology

Total patient number

N = 63

Number of patients with AEs (any grade), n (%)

29 (45.5)

Cause of discontinuation, n (%)

PD

37 (58.7)

AE

12 (19.0)

The detail of AEs (G3 or more), n (%)

15 (23.8)

Anorexia

3 (4.8)

Myocardial infarction

2 (3.2)

Liver dysfunction

2 (3.2)

Diarrhea

2 (3.2)

Pneumonia

2 (3.2)

Renal insufficiency

1 (1.6)

Proteinuria

1 (1.6)

Glossitis

1 (1.6)

Shingles

1 (1.6)

Aspiration pneumonia

1 (1.6)

Artery mural thrombus

1 (1.6)

  1. PD progressive disease, AE adverse event, G grade.