Table 2 Summary of the AUC, sensitivity, and specificity for CRP, CA125, and HE4 in the diagnosis of EOC.
From: Clinical usefulness of high levels of C-reactive protein for diagnosing epithelial ovarian cancer
AUC | 95% CI | Sensitivity (%) | Specificity (%) | |
|---|---|---|---|---|
CRP | 0.89 | 0.84–0.94 | 82.4 | 88.9 |
CA125 | 0.93 | 0.89–0.96 | 79.1 | 88.9 |
HE4 | 0.71 | 0.63–0.79 | 62.6 | 81.4 |
CRP + CA125 | 0.95 | 0.92–0.98 | 86.8 | 90.1 |
CRP + HE4 | 0.89 | 0.84–0.94 | 82.4 | 87.6 |
CA125 + HE4 | 0.93 | 0.89–0.96 | 78.0 | 87.6 |
CRP + CA125 + HE4 | 0.96 | 0.92–0.98 | 87.9 | 91.3 |
