Table 3 Determination of cut-off values for CRP, CA125, and HE4.

From: Clinical usefulness of high levels of C-reactive protein for diagnosing epithelial ovarian cancer

 

Cut-off value

Sensitivity at cut-off value (%)

Specificity at cut-off value (%)

PPV at cut-off value (%)

NPV at cut-off value (%)

Accuracy at cut-off value (%)

CRP

9.8 mg/L

78.0

96.3

97.2

77.8

86.6

CA125

26 U/ml

83.5

76.5

80.1

80.0

80.2

HE4

97 pmol/L

53.9

76.6

66.1

64.1

64.5

  1. PPV positive predictive value; NPV negative predictive value.