Table 2 Correlation between CRF content in eosinophils and clinical parameters.

From: Overexpression of corticotropin-releasing factor in intestinal mucosal eosinophils is associated with clinical severity in Diarrhea-Predominant Irritable Bowel Syndrome

CRF/granule

rs

P value

FDR

HC

IBS-D

Intensity of pain

0.799

0.0002

0.001***

–

17

Frequency of pain

0.3812

0.1313

0.184

–

17

IBS Severity

0.5343

0.0291

0.058*

–

17

Distention

0.4856

0.0499

0.087*

–

17

Dyspepsia

0.3114

0.2454

0.312

–

17

Bowel movements

0.6161

0.0013

0.005**

7

17

Stool form

0.6055

0.0017

0.005

7

17

Stress (last month)

0.6557

0.0001

0.001***

12

17

Stress (last year)

0.3478

0.0645

0.100

12

17

Depression score

0.7191

 < 0,0001

0.001***

12

17

Eosinophil /mm2

0.1404

0.4849

0.522

11

16

Atopy

− 0.06747

0.7433

0.743

10

16

Sex

0.4435

0.016

0.037*

12

17

  1. P values considered significant are shown in bold. P value adjusted (false discovery rate (FDR)): *P < 0.05; **P < 0.01 and ***P < 0.001. HC, healthy controls; IBS-D, diarrhea-predominant IBS; A FDR < 10% was accepted as significant.
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