Table 3 Correlation between CRFR1 gene expression in jejunal samples from HC and IBS-D and clinical parameters. P values considered significant are shown in bold. P value adjusted (false discovery rate (FDR)): *P < 0.05; **P < 0.01. HC, healthy controls; IBS-D, diarrhea-predominant IBS; A FDR < 10% was accepted as significant.

From: Overexpression of corticotropin-releasing factor in intestinal mucosal eosinophils is associated with clinical severity in Diarrhea-Predominant Irritable Bowel Syndrome

CRHR1 expression

rs

P value

FDR

HC

IBS-D

Intensity of pain

− 0.6157

0.0109

0.0681*

–

17

Stool form

− 0.5743

0.0042

0.0357**

7

17

Stress (last year)

− 0.5561

0.0026

0.0357**

12

16

Depression score

− 0.4646

0.0143

0.0620*

11

16

Stress (last month)

− 0.3552

0.075

0.2108

11

16

Back to article page