Figure 2 | Scientific Reports

Figure 2

From: Structural and functional characterization of M. tuberculosis sedoheptulose- 7-phosphate isomerase, a critical enzyme involved in lipopolysaccharide biosynthetic pathway

Figure 2

Small angle X-ray scattering analysis on MtbGmhA enzyme. (A) SAXS intensity profile of MtbGmhA. The inset shows linear fit to Guinier region of measured data. (B) Kratky plot of MtbGmhA. (C) The P(R) curves computed for MtbGmhA indicating the frequency distribution of interatomic vectors in predominant scattering species. (D–F) Fitting of MtbGmhA tetramer (closed state) in shape restored from dummy atom modeling using small angle X-ray scattering data and shown after every 90° rotation along Y-axis. Fitting of MtbGmhA tetramer (open state) in shape restored from dummy atom modeling using small angle X-ray scattering data and shown after every 90° rotation.

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