Table 1 Tissue characteristics of the 42 tumor samples obtained from 21 patients.

From: Macroscopic fluorescence-lifetime imaging of NADH and protoporphyrin IX improves the detection and grading of 5-aminolevulinic acid-stained brain tumors

Patient ID

Diagnosis

Samples obtained

ALA fluorescence

Tumor grade

1

Diffuse astrocytoma

TUM/TUM/TUM

− /−/ −

LGG

2

Diffuse astrocytoma

INF/INF

− / −

LGG

3

Oligodendroglioma

INF/INF

− / −

LGG

4

Anaplastic astrocytoma

TUM/TUM

− / + 

HGG

5

Anaplastic oligodendroglioma

NPL

HGG

6

Glioblastoma

INF/TUM

− / + 

HGG

7

Glioblastoma

INF/NEC

− / + 

HGG

8

Glioblastoma

INF/TUM

− / + 

HGG

9

Glioblastoma

INF/NEC

 + / + 

HGG

10

Glioblastoma

NEC/TUM

− / + 

HGG

11

Glioblastoma

NEC/TUM

− / + 

HGG

12

Glioblastoma

INF/TUM

− / + 

HGG

13

Glioblastoma

INF

 + 

HGG

14

Glioblastoma

TUM

 + 

HGG

15

Glioblastoma

TUM

 + 

HGG

16

Glioblastoma

INF/TUM

 + / + 

HGG

17

Glioblastoma

NPL/TUM

− / + 

HGG

18

Metastases (primary: lung)

REA/INF/TUM

 + /−/ + 

MET

19

Metastases (primary: lung)

REA/NEC

 + / −

MET

20

Metastases (primary: lung)

REA/REA/NEC

− / + / −

MET

21

Metastases (primary: heart)

REA/NEC/TUM

 + /−/ + 

MET

 

Total: 42

(NPL–2; REA–5;

INF–12; NEC–7;

TUM–16)

ALA positive:

21

ALA negative:

21

Partition:

LGG–3 (7)

HGG–14 (24)

MET–4 (11)

  1. The table shows the distribution of tissue samples obtained during fluorescence guided brain tumor resection with the patient diagnosis, the tissue histology, 5-ALA fluorescence status during surgery (visible to surgeon: +/ not visible to surgeon: −) as well as the confirmed tumor grade (LGG: low grade glioma, HGG: high grade glioma, MET: brain metastases). Bold entries specify the representative tissue samples which are shown in Fig. 1.