Figure 1 | Scientific Reports

Figure 1

From: Mycobacterial Hsp65 antigen delivered by invasive Lactococcus lactis reduces intestinal inflammation and fibrosis in TNBS-induced chronic colitis model

Figure 1

Representation of the experimental design for 2,4,6-trinitrobenzene sulfonic acid (TNBS)-induced chronic colitis. Intestinal inflammation was induced by TNBS in BALB/c µwas induced by weekly (on days 8, 15, 22, 29, 36 and 43) intrarectal administration of solutions with increasing concentrations of TNBS in 50% ethanol [0.75%, 1.5% and 2.5% TNBS (wt/vol)]. The mice received four intragastric administrations of bacterial suspension containing 1 × 109 CFUs per week for 6 consecutive weeks. On day 54, all the mice were euthanized.

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