Figure 1

Baseline expression profile of PVEC and ABEC highlights the distinct identity of these vascular beds. (a) Hierarchical clustering indicates total segregation between PVEC and ABEC. (b) Heatmap of the top 50 genes that were significantly different in PVEC vs. ABEC, based on fold change. Red indicates genes with higher expression and blue indicates genes with lower expression in PVEC vs. ABEC. (c) Volcano plot encompassing all analyzed genes, depicted as dots. Black dots represent genes that were not significantly different, while gray dots represent genes that were significantly different in PVEC vs. ABEC, based on fold change (FC) > 2 and p-value < 0.05. Highlighted in blue dots are the genes that were most significantly lower, and in red dots genes that were most significantly higher in PVEC vs. ABEC.